523Mesothelioma Cancer Patients Might Find Hope from Genetic Therapy Clinical Trials
posted on July 20th, 2009
Doctors who specialize in cancer treatment decide what kind of treatment to go with to their patient. The options are endless. There is no standard treatment course for mesothelioma patients. Mesotheliomas lack of agreed-upon treatment is due to low a treatment success rate, rareness, a high mortality rate and a small number of studies providing meaningful stats.
While prospects for patients with mesothelioma have been bleak, doctors have been making progress. Customary treatments for cancer are surgery (removing the tumor and the tissue that surrounds it), radiation (killing the cancerous cells with radiation), and chemotherapy (poisoning the cancerous cells.) Each one of these methods have problems. Traditional radiation therapy has not worked well with mesothelioma patients. Researches, concerned about damage to healthy tissue, are looking for ways to aim radiation directly at tumors.
Surgery takes out the mesothelial cancerous tissue around the tumor. It is a grueling surgery with unknown benefits to patients. Common chemotherapy drugs that work on other types of cancer usually do not work on mesothelioma, and different combinations of chemotherapy drugs have been tried without a lot of success. Similar to radiation, focus in research is focusing on treating the physical location of the tumor with emphasis on the pleural cavity.
The death rate for mesothelioma is so high that many of even the most sophisticated techniques in cancer treatment are tried out on patients. Such treatments include anti-angiogenesis drugs like thalidomide and biologic therapies agent interleukin 2. A new drug that has shown results in improving survival is pemetrexed (brand name Alimta).
Oncologists consider the stage of mesothelioma, the location of the tumor, the patient’s age and state of health at the time. Two exotic ways of attacking mesothelioma are gene therapy and photodynamic therapy. Clinical trials using these techniques are being offered to some of those who have mesothelioma.
